Barely Significant
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Treatment Optimization in Linac-Based SBRT for Localized Prostate Cancer: A Single-Arc versus Dual-Arc Plan Comparison.

Cancers (Basel) · 2023 · PMC10778084 · PMID 38201441

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showed a trendno p-value reported
[ 40 ] retrospectively analyzed 148 plans over eight years using the PlanIQTM software for learning curve evaluation and showed a trend of improvement in the quality of the plans over each successive year.

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A post-hoc analysis of patients treated within the MIRAGE trial [ 33 ] identified that an increased number of patients experienced G2+ urinary toxicity when they received higher intermediate doses in the bladder and had larger portions of the trigone exposed to elevated doses, although the trend did not reach statistical significance.

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