Investigating the Mitoprotective Effects of S1P Receptor Modulators Ex Vivo Using a Novel Semi-Automated Live Imaging Set-Up.

Int J Mol Sci · 2023 · PMC10778583 · PMID 38203434

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reached borderline significanceno p-value reported

Due to the low sample size of computable fractions ( n = 12), this effect was not significant, but H 2 O 2 + fingolimod reached borderline significance when compared to H 2 O 2 alone (H 2 O 2 + fingolimod vs.

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showed a trendno p-value reported

Treatment with siponimod showed a trend to prevent the oxidative stress-induced decrease in mitochondrial displacement ( Figure 3 B).

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