SARIFA as a new histopathological biomarker is associated with adverse clinicopathological characteristics, tumor-promoting fatty-acid metabolism, and might predict a metastatic pattern in pT3a prostate cancer.

BMC Cancer · 2024 · PMC10785487 · PMID 38216952

Europe PMC DOI

hedged sentences

0.0660

closest p · 1.3× alpha

0.3500

boldest claim

The sentences

a clear trendp = 0.066so close (0.05 < p ≤ 0.1)

The difference in distant lymph node metastasis between SARIFA-positive and SARIFA-negative groups showed a clear trend and just failed to show statistical significance ( p = 0.066).

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did not reach statistical significancep = 0.35not close (p > 0.1)

Although the curves seemingly exhibited distinct separation, indicating a worse clinical course for SARIFA-positive cases, this association did not reach statistical significance (p = 0.35; HR of 1.290, 95% CI: 0.758–2.196).

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