Preoperative IL-8 levels as prognostic indicators of overall survival: an extended follow-up in a prospective cohort with colorectal liver metastases.

BMC Cancer · 2024 · PMC10792859 · PMID 38233759

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0600

boldest claim

The sentences

did not reach statistical significancep = 0.056so close (0.05 < p ≤ 0.1)

Among these factors, only synchronous metastasis demonstrated a significant association with disease-free survival, while the positive lymph node status did not reach statistical significance ( p = 0.056).

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showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Preoperatively increased Interleukin 6 (IL-6) showed a trend towards worse survival (HR 2.13 95%CI 0.97 – 4.68; p = 0.06), as did synchronous liver metastases (HR 2.5; 95% CI 0.93 – 6.71; p = 0.07).

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