Expression Pattern and Prognostic Significance of the Long Non-Coding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 in Chronic Lymphocytic Leukemia.

Int J Mol Sci · 2024 · PMC10815316 · PMID 38255996

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.051so close (0.05 < p ≤ 0.1)

unfavorable) showed a trend toward the independent association of MALAT1 expression with TTFT in U-CLL (hazard ratio (HR) = 0.581, 95% CI = 0.337−1.002, p = 0.051).

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did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

When we grouped patients with low and intermediate and high and very high risk together, we observed a trend towards a higher frequency of high and very high CLL-IPI risk in the MALAT1 high group in comparison to the MALAT1 low group when the whole cohort was analyzed, but this difference did not reach statistical significance ( p = 0.08, Fisher exact test).

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