Discussion In summary, we found a U-shaped association between BMI and physiological age, where underweight and obesity were associated with the highest physiological age, except in those aged ≥ 85 years, where the association between BMI and FI was not statistically significant, but showed a trend indicating a lower physiological age with higher BMI levels.
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Interplay of body mass index and metabolic syndrome: association with physiological age from midlife to late-life.
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The sentences
Our study did not replicate this overall inverse association between BMI and physiological age – the closest we found was a negative association between BMI and FI after age 85, which failed to reach statistical significance.