Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape.

Importantly, we detected a strong trend for increased abundance of cleaved caspase 3-positive cells in eWAT of obese IF mice (Fig. 2 d, e ).

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Interestingly, transcript levels of genes encoding for LAM markers like Mmp12 , Trem2 , Lipa , and Gpnmb showed a clear trend to increased expression in response to IF when measured in bulk eWAT (Fig. 1k ).

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