MMP-11 expression in early luminal breast cancer: associations with clinical, MRI, pathological characteristics, and disease-free survival.

Using the Cox Proportional Hazards model, accounting for MMP-11 expression and other vital clinical and pathological prognostic factors, only two variables showed significant or near-significant associations with reduced DFS: elevated Ki67 (HR = 1.12, 95% CI [1.03–1.21], p = 0.01) and high MMP-11 expression (HR = 1.02, 95% CI [1.00-1.04], p = 0.05).

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MMP-11 immunohistochemical score demonstrates a suggestive trend in association with disease-free survival, independent of Ki67 and other traditional prognostic factors.

also in 33 other papers