Modification of Huntington's disease by short tandem repeats.

14 , 15 , 49 , 74 Interestingly, one candidate modifier that showed a trend of association 66 , 75 and was replicated by GWAS is TCERG1, which harbours a complex coding hexamer repeat that appears to be the source of the influence on HD age-at-onset. 76 Unfortunately, the hexamer repeat with potential association was not imputed in our data because this repeat was not present in the imputation reference panel that we used.

also in 53,322 other papers

We observed nominally significant P -values for the association of some loci with HD residual age-at-onset ( Supplementary Table 1 ), but when these were corrected for the gene size and number of SNPs in the region, none remained statistically significant.

also in 7,732 other papers