Our analyses showed a trend for increasing adverse effects with q12h dosage than q24h dosage that is weakly significant without a strong effect of further reducing seizure frequency, suggesting clinicians should begin zonisamide with q24h dosing.
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A retrospective study of the efficacy of zonisamide in controlling seizures in 57 cats.
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The sentences
Our analyses showed a trend for increasing adverse effects with q12h dosage than q24h dosage that is weakly significant without a strong effect of further reducing seizure frequency, suggesting clinicians should begin zonisamide with q24h dosing.