HER3 overexpression: a predictive marker for poor prognosis in advanced ALK-positive non-small cell lung cancer treated with ALK inhibitors.

Due to the limited number of cases with high expression, paired comparisons did not reach statistical significance.

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However, the patients with high EGFR or HER3 expression in primary tumor cells showed a trend toward poorer outcomes, although these findings did not reach statistical significance (P=0.207 and 0.132, respectively; Figure 3B,3C ).

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