A trend towards stabilisation in 6MWD was observed in bosentan group, but it did not reach statistical significance (−25.9±56.7 m vs −53.1±66.9 m, p=0.42).
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Vasoactive drugs for the treatment of pulmonary hypertension associated with interstitial lung diseases: a systematic review.
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The sentences
Patients treated with bosentan showed a trend towards increase in 6MWD, compared with a slight decrease in the placebo arm.