MicroRNA-190b Targets RFWD3 in Estrogen Receptor-Positive Breast Cancer.

We see a clear trend of miR-190b downregulating RFWD3, and we see negative correlation in the expression data from TCGA.

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Using omics data in DepMap from the Broad institute, 24 we also see a negative trend between miR-190b expression and RFWD3 protein levels in breast cancer cell lines ( Supplemental Figure 5A ), which is in line with the western blot findings.

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