An evolutionarily conserved olfactory receptor is required for sex differences in blood pressure.

We confirm the previously published association of the lead variant in the total sample, with the association for DBP still being highly significant in the UKB data alone ( P = 4.27 × 10 −5 ; N = 423,655).

also in 132,142 other papers

The association is nominally significant ( P = 0.053) within females, with the minor allele A increasing DBP by +6.28 mmHg for female carriers (AG) versus female non-carriers (GG).

also in 7,732 other papers

Results with other ligands [which we have previously identified for the WT receptor ( 33 )] did not reach statistical significance in the absence of Golf ( Fig. 8C ).

also in 111,027 other papers