Effects and Mechanisms of Exercise on Brain-Derived Neurotrophic Factor (BDNF) Levels and Clinical Outcomes in People with Parkinson's Disease: A Systematic Review and Meta-Analysis.

Brain Sci · 2024 · PMC10968162 · PMID 38539583

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failed to reach statistical significanceno p-value reported

[ 34 ] showed an increase in serum BDNF in healthy controls and people with PD, but this increase failed to reach statistical significance.

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a clear trendno p-value reported

The limited dataset did not allow for a formal analysis of exercise intervention dosage, and Table 2 did not reveal a clear trend for higher effect sizes with increased exercise dosage.

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