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PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer.

Cells · 2024 · PMC10968744 · PMID 38534371

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showed a trendno p-value reported
32 days) and showed a trend towards extended survival compared to DT2216 (median survival: 104 vs. 94 days) ( Figure 4 b).

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Additionally, 753b at this dosage led to a trend of extending median survival compared to DT2216; however, the difference did not reach statistical significance.

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