Correlation between ADC, Tumor Grades, and Clinicopathological Variables There was a near-significant difference ( p = 0.050) between the ADCs of well (mean p10 1355 μm 2 /s), moderately (mean p10 1052 μm 2 /s), and poorly differentiated tumors (mean p10 1052 μm 2 /s).
Overall survival was significantly lower for poor tumor differentiation (HR 0.418, 95% CI 0.178–0.985, p = 0.046) and non-glandular Kalimuthu patterns (HR 0.352, 95% CI 0.151–0.823, p = 0.016) and showed a trend for poorer survival for Adsay G3 (HR 0.498, 95% CI 0.223–1.115, p = 0.090) after correction for age, tumor location, and stage. 4.