MMR vaccination induces trained immunity via functional and metabolic reprogramming of γδ T cells.

This change appeared to be driven mainly by an increase in myeloid cells (neutrophils and monocytes), although the comparison did not reach statistical significance for the individual cell types.

also in 111,027 other papers

Unstimulated Vδ2 T cells showed a trend toward lower expression of the degranulation marker CD107a after MMR vaccination ( Supplemental Figure 6C ); this effect was not present in CD3/CD28-stimulated Vδ2 T cells, which showed no difference between time points in the percentage of cells staining positive for CD107a, GZMB, or perforin ( Figure 5C ).

also in 53,322 other papers