Autologous human preclinical modeling of melanoma interpatient clinical responses to immunotherapeutics.

In response to nemvaleukin treatment, these subsets of T cells showed a trend of active proliferation, as signified by Ki-67 expression, without any sign of GVHD for more than 4 weeks.

also in 53,322 other papers

Interestingly, combining nemvaleukin with anti-PD-1 tended to increase the population of CD8 + CD45RA + CCR7 + CD28 + CD95 + stem cell memory T cells (Tscm) in splenocytes and TIL compared with vehicle control; however, this difference did not reach statistical significance ( figure 5D ).

also in 111,027 other papers