Chitogel with deferiprone following endoscopic sinus surgery: improved wound healing and microbiome.

The difference was statistically significant for the frontal sinus ( p = 0.04), and showed a strong trend for sphenoid ( p = 0.09) and maxillary ( p = 0.26) sinuses.

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There was an observed trend of increase in Faith's Phylogenetic Diversity after 12 weeks in the treated sinus compared with the untreated sinus in the Chitogel with 1 mM deferiprone and Chitogel with 5 mM deferiprone groups ( p = 0.2 and p = 0.16).

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All three treatments showed a trend of decreasing scores after 6 and 12 weeks post-operatively.

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