A High Vitamin C Micronutrient Supplement Is Unable to Attenuate Inflammation in People with Metabolic Syndrome but May Improve Metabolic Health Indices: A Randomised Controlled Trial.

Antioxidants (Basel) · 2024 · PMC11047647 · PMID 38671852

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.1800

boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

LDL cholesterol concentrations showed a trend towards a decline over the duration of the study relative to placebo (Δ−0.2 [95%CI −0.5, 0.1] mmol/L, p = 0.08).

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did not reach statistical significancep = 0.18not close (p > 0.1)

The baseline IL-6 concentration was 9.9 (6.7, 15) pg/mL and although the micronutrient group was trending towards a lower concentration over time (Δ−2.9 [95%CI −7.2, 1.4] pmol/L), this did not reach statistical significance ( p = 0.18; Table 4 ).

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