TOP CAR with TMIGD2 as a safe and effective costimulatory domain in CAR cells treating human solid tumors.

< 0.05) due to few genes meeting the log 2 fold change cutoff, overrepresented pathways approaching significance ( P adj. < 0.1) described lysosomal and vacuole pathways ( Fig. 6C ).

also in 2,640 other papers

Last, we found that, while both B7-H3 CAR-T cells showed a trend of decreasing CD4 + T cells and increasing CD8 + T cells, B7-H3.TMI.ζ CAR-T cells showed significantly lower CD4 + T cells, significantly higher CD8 + T cells, and a significantly higher CD8/CD4 T cell ratio compared to B7-H3.28.BB.ζ CAR-T cells beginning on day 13 ( Fig. 7C ).

also in 53,322 other papers