near-significantP = 0.002
Rearing events also showed significant or near-significant increases when analyzed separately within binned intervals (0 to 10 min, P = 0.002; 10 to 20 min, P = 0.046; 20 to 30 min, P = 0.074) ( Fig. 3 C ).
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Human mutations in high-confidence Tourette disorder genes affect sensorimotor behavior, reward learning, and striatal dopamine in mice.
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0.0020
0.1390
The sentences
showed a trendP = 0.09
Celsr3 C1906Y/+ females were more active and traveled more total distance compared to controls [F(1, 30) = 6.4, P = 0.017] , whereas Celsr3 C1906Y/+ males showed a trend-level effect [F(1, 30) = 2.9, P = 0.09] ( Fig. 3 B ).
a weak trendP = 0.139
Celsr3 C1906Y/+ females made more center zone entries over time [Time × genotype effect: F(2, 60) = 5.693, P = 0.005], whereas males showed a weak trend [Time × genotype effect: F(2, 60) = 2.04, P = 0.139] ( SI Appendix , Fig.