Spatial variations in the osteocyte lacuno-canalicular network density and analysis of the connectomic parameters.

Although the data scatters substantially (R 2 < 0.4), there is a clear trend that the prevalence of both long canaliculi and tree-like nodes decreases with increasing canalicular densities.

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Within the mature intercortical tissue, the posterior cortex of the loaded limb showed a trend of increasing canalicular density which decreased at the interface with newly formed tissue (blue lines at the green dash lines and nearby).

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