Polymorphisms of DNA Repair Genes in Thyroid Cancer.

Int J Mol Sci · 2024 · PMC11172789 · PMID 38892180

Europe PMC DOI

hedged sentences

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

showed a trendp = 0.057so close (0.05 < p ≤ 0.1)

on Caucasians from the Portuguese population showed a trend toward increased risk of thyroid cancer for people who are homozygous for the RAD51 rs180132 polymorphic allele variant (adjusted OR = 1.9; 95% CI = 1.0–3.5; p = 0.057) [ 44 ].

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did not reach statistical significanceno p-value reported

In Iran, rs25489 analysis showed a 1.42-fold increase in the risk of differentiated thyroid cancer (DTC) demonstrated for the dominant feature GG + GA compared to AA (OR = 1.42; 95% CI = 0.76–2.68; p = 0.275), but the result did not reach statistical significance [ 28 ].

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