Lung tumor discrimination by deep neural network model CanDo via DNA methylation in bronchial lavage.

In contrast, the noncancer group exhibited lower methylation rates, showing a highly significant statistical difference ( p < 0.00005, Figure 2 A, EXdata 2.

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It is noteworthy that a highly significant strong correlation among the methylation patterns of the 11 features was observed, whereas the correlation between age and all 11 features did not reach statistical significance ( Figure 3 D, and Table S6 ).

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Our findings revealed a significant trend of increased methylation levels at most CpG sites in the 73 cancer patients compared to the 45 patients diagnosed with non-cancerous conditions through pathology ( Figure S2 , EXdata 1.

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