Expression of Cathepsin D in early-stage breast cancer and its prognostic and predictive value.

Breast Cancer Res Treat · 2024 · PMC11182851 · PMID 38578521

Europe PMC DOI

hedged sentences

0.0070

closest p · 0.1× alpha

0.0900

boldest claim

The sentences

highly significantp < 0.007actually significant

Statistical analysis demonstrated a highly significant association of Cathepsin D with poor prognostic variables including high tumour grade ( p < 0.007) and poor NPI ( p = 0.002).

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showed a trendp = 0.084so close (0.05 < p ≤ 0.1)

Unexpectedly, our study did not find a significant correlation between tumour stage and Cathepsin D expression but it showed a trend ( p = 0.084).

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did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

Although the previous study did not reach statistical significance ( p = 0.09), it supports our findings and warrants further investigation [ 32 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.