Fibulin-2 is an extracellular matrix inhibitor of oligodendrocytes relevant to multiple sclerosis.

Some Notch-related genes ( Maml2 , Rbpj ) showed an upward trend in WT mice ( Figure 6L ); however, it did not reach statistical significance owing to the small size of this population especially in WT mice.

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While total axon density showed a trend toward a higher level in FBLN2-deficient mice, these differences did not reach statistical significance.

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