A small-molecule microtubule-stabilizing agent safely reduces Aβ plaque and tau pathology in transgenic mouse models of Alzheimer's disease.

Alzheimers Dement · 2024 · PMC11247666 · PMID 38884283

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a strong trendno p-value reported

CNDR‐51997 attenuated axonal dystrophy and gliosis in a tauopathy mouse model, with a strong trend toward reduced hippocampal neuron loss.

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did not reach statistical significanceno p-value reported

However, these changes did not reach statistical significance.

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