Targeted panel sequencing of pharmacogenes and oncodrivers in colorectal cancer patients reveals genes with prognostic significance.

Similarly, the rest of the observed associations showed a clear trend although p-values were statistically insignificant.

also in 12,136 other papers

KRAS mutation counts followed an increasing trend with grade (G1 < G2 < G3).

also in 37,734 other papers

Although patients with wild-type for rs2444274 (intron) in RIF1 had worse RFS and OS than carriers of heterozygous or variant genotypes, these associations did not pass the FDR adjustment (p crude =0.009/p adj =0.054 for RFS) or remained borderline significant (p crude =0.006/p adj =0.043 for OS) (Fig. 5 e, f).

also in 6,883 other papers

3 e) and weakly significant before FDR adjustment in all patients (p crude =0.025/p adj =0.070, Fig. 3 f).

also in 779 other papers