Impact of Growth Conditions on High-Throughput Identification of Repurposing Drugs for <i>Pseudomonas aeruginosa</i> Cystic Fibrosis Lung Infections.

A trend indicating lower aminoglycoside activity was observed when tested under CF-like conditions, although it did not reach statistical significance (not active drugs: 57.1% vs. 28.6%; excellent activity: 14.3% vs. 28.6%, respectively, in CF-like and enriched conditions; p > 0.05).

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Sulphonamides showed a trend of higher activity under CF-like conditions, although this trend was not statistically significant.

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