Systematic Review and Meta-analysis of Clinical Outcomes Following Meniscus Repair in Patients 40 Years and Older.

Seven comparative studies also provided data amenable for meta-analysis comparing failure rates between older and younger patients and revealed there were trends for older patients to be less likely to experience failure; however, this difference did not reach statistical significance ( Figure 3 ) (RR, 0.69 [95% CI, 0.41-1.16]; P = .1613). 2 , 7 , 22 , 42 , 46 , 51 , 52 In addition, Lyman et al 30 reported on relevant data that were not amenable to meta-analysis, observing that patients aged ≥40 years were less likely to experience failure (ie, were less likely to require future meniscectomy) compared with patients aged <20 years after an isolated meniscal repair (hazard ratio [HR], 0.53 [95% CI, 0.40-0.70]; P < .001) but not after meniscal repair with concomitant ACL reconstruction (HR, 0.99 [95% CI, 0.71-1.37]; P = .927).

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Meta-analysis of comparative studies showed a lower risk of a meniscal repair failure in “older” than younger patients; however, this failed to reach statistical significance (relative risk [RR], 0.73 [95% CI, 0.44-1.21]; P = .2205) ( Figure 2 ).

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