The effect of different dialysate sodium concentrations on ambulatory blood pressure in hemodialysis patients: a prospective interventional study.

Finally, in one of the first studies that aimed to improve BP control in hemodialysis patients using lower dialysate sodium (gradual lowering from 140 mmol/L to 135 mmol/L at a rate of 1 mmol/L every 3–4 weeks) combined with dietary salt restriction (<6 g sodium chloride/day), pre-dialysis SBP/DBP showed a clear trend to reduce with the lower sodium concentrations without changes in dry weight [ 31 ].

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IDWG increased with higher dialysate sodium concentrations (2.62 ± 0.92 kg with 137 meq/L vs 2.67 ± 1.3 kg with 139 meq/L vs 3.06 ± 1.17 kg with 141 meq/L, P = 0.076), although this difference did not reach statistical significance.

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