Although there was no statistically significant difference between the two fixed dosages, 480 mg Q4W showed a trend of slightly better efficacy.
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Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses.
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The sentences
In the second-line cohort of the 480 mg group, there was a trend towards improved PFS and OS; however, this did not reach statistical significance.