The impact of biologic agents on cardiovascular risk factors in patients with rheumatoid arthritis: A meta analysis.

PLoS One · 2024 · PMC11361434 · PMID 39208032

Europe PMC DOI

hedged sentences

0.7600

closest p · 15.2× alpha

0.7600

boldest claim

The sentences

showed a trendP = 0.76not close (p > 0.1)

The pooled effect size showed a trend towards reducing total cholesterol levels in the biologic treatment group (MD = -0.03, 95% CI: [-0.21, -0.15], P = 0.76), (z = 0.30, P = 0.76).

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did not reach statistical significanceno p-value reported

In the subgroup analysis of different drug treatments, no heterogeneity was observed, and the pooled effect size indicated a trend towards a decrease in total cholesterol levels in the biologics with DMARDs treatment group, but it did not reach statistical significance ( S2 Fig ).

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