Autoimmune thyroid disease modifies the clinical expression of hand osteoarthritis in older people: a third National Health and nutrition examination survey study.

Additionally, TgAb as a continuous variable was not significantly associated with symptomatic hand OA regardless of whether controlling for covariates or not, although there was a positive trend toward association ( p = 0.071 and p = 0.094, respectively) ( Table 5 , models 1 and 2).

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TgAb showed a trend toward being positively associated with symptomatic hand OA ( p < 0.10).

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However, the association of TPOAb with symptomatic hand OA did not reach statistical significance when stratified into quartiles, and we speculate that a larger sample size might be required to further explore a dose-dependent association.

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