The associations of the ABCC2 rs717620 and PDE1C rs30561 with HIV non-suppression did not reach statistical significance, but it had an additive effect when combined with the S LC28A2 rs11854484 SNP.
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Pharmacogenetic determinants of tenofovir diphosphate and lamivudine triphosphate concentrations in people with HIV/HBV coinfection.
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The sentences
There was also an additive effect of the SNP with two other SNPs ( ABCC2 rs717620 and PDE1C rs30561) that showed a trend toward HIV non-suppression.