A pilot pragmatic randomized controlled trial of a nicotine metabolite ratio-guided smoking cessation intervention in a lung health and screening program.

However, there was a difference approaching significance in treatment matching such that 29 % of the standard care and 55 % of the NMR-guided care participants reported taking the optimal medication based on their NMR status (OR 2.93, 95 % CI [0.75, 11.49; p = 0.122])).

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Participants in the NMR-guided care treatment arm showed a trend towards a higher treatment matching than participants in standard care overall (55 % vs. 29 %) and among participants who reported taking medication (79 % vs. 45 %).

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