Metabolic score for insulin resistance as a predictor of mortality in heart failure with preserved ejection fraction: results from a multicenter cohort study.

In addition, we found that although the interaction of the prognostic efficacy of METS-IR across the three subgroups did not reach statistical significance ( P > 0.05), the trend suggested seemingly opposite patterns for all-cause mortality and CV death.

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The HRs of IHD for METS-IR quartiles 1–4 were as follows (after adjusting for potential confounders): 1.00, 1.62 (95% CI 1.04–2.53), 1.87 (95% CI 1.20–2.91), and 2.11 (95% CI 1.35–3.30), thus indicating a clear trend of increased risk with elevated METS-IR levels [ 12 ].

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