Identification of PFKFB3 as a key factor in the development of colorectal cancer and immunotherapy resistance.

Clin Exp Med · 2024 · PMC11390783 · PMID 39261380

Europe PMC DOI

hedged sentences

0.0909

closest p · 1.8× alpha

0.1000

boldest claim

The sentences

did not reach statistical significanceP = 0.0909so close (0.05 < p ≤ 0.1)

Although the association in the CTLA-4 inhibitor cohort did not reach statistical significance ( P = 0.0909), there was a trend toward shorter OS ( HR = 1.66).

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near-significantP < 0.1so close (0.05 < p ≤ 0.1)

Additionally, PFKFB3 showed a near-significant relationship with OS in stage III and female subgroups ( P < 0.1).

also in 2,306 other papers

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