HLA-A01 and HLA-B27 Supertypes, but Not HLA Homozygocity, Correlate with Clinical Outcome among Patients with Non-Small Cell Lung Cancer Treated with Pembrolizumab in Combination with Chemotherapy.

Cancers (Basel) · 2024 · PMC11394546 · PMID 39272960

Europe PMC DOI

hedged sentence

0.0660

closest p · 1.3× alpha

0.0660

boldest claim

The sentences

did not reach statistical significancep = 0.066so close (0.05 < p ≤ 0.1)

showed a trendp = 0.066so close (0.05 < p ≤ 0.1)

The presence of the HLA-A03 supertype showed a trend in association with protection against developing irAEs that did not reach statistical significance (RR = 0.35, 95%CI 0.12–0.96, p = 0.066).

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