Causal association of inflammatory bowel disease with sarcoidosis and the mediating role of primary biliary cholangitis.

Similarly, excluding MR-Egger (OR = 1.037, 95% CI: 0.865–1.244, p = 0.695) and the Simple model (OR = 1.150, 95% CI: 0.988–1.339, p = 0.076), other methods supported the nominally significant causal association between CD and PBC (weighted median OR = 1.102, 95% CI: 1.020–1.192, p = 0.014; weighted model OR = 1.108, 95% CI: 1.026–1.196, p = 0.011) ( Figure 2 ).

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Other methods did not reach statistical significance for the causal association between IBD and PBC.

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