showed a trendp = 0.08
In the third study [ 7 ], rs2228595, which showed un-replicated evidence for increased frequency of the T allele in the earlier German study [ 5 ] showed a trend for association of the C allele, (p = 0.08), in a sample of white European American siblings, but not in a second sample of 67 white European American families with one or more affected offspring, or in the two samples combined (616 transmissions observed, 612 expected).