Barely Significant
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Role of circulating T follicular helper subsets following Ty21a immunization and oral challenge with wild type <i>S</i>. Typhi in humans.

Front Immunol · 2024 · PMC11424897 · PMID 39328410

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showed a trendp ≤ 0.1so close (0.05 < p ≤ 0.1)
Further analysis of the data by AUC revealed that during the immunization phase, the expression of CCR7 showed a trend (p ≤ 0.1) to increase in cT FH 2 but not cT FH 1 or cT FH 17 in TD compared with NoTD participants ( Supplementary Figures S5A-C ).

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However, we noted that following challenge (D0 to D7), both cT FH 2 and cT FH 17 frequencies were lower in TD than in NoTD participants but this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.