Type 2 Biomarkers and Their Clinical Implications in Bronchiectasis: A Prospective Cohort Study.

Lung · 2024 · PMC11427600 · PMID 38884647

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0980

boldest claim

The sentences

nearing significancep = 0.050actually significant

Clinically, the BEC ≥ 300 cells/μL group showed a trend towards more frequent exacerbations, nearing significance (p = 0.050), whereas patients with FeNO ≥ 25 ppb experienced significantly fewer exacerbations (p = 0.048).

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showed a trendp = 0.054so close (0.05 < p ≤ 0.1)

BEC ≥ 300 cells/μL showed a trend towards reduced FEV 1 /FVC (p = 0.054), while high FeNO was associated with normal lung function (p = 0.033) and less radiological severity (p = 0.012).

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did not reach statistical significancep = 0.098so close (0.05 < p ≤ 0.1)

The combined low BEC and high FeNO indicated a decreased risk in univariable analysis but did not reach statistical significance in the multivariable analysis (HR: 0.459, p = 0.098).

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