First-line treatment of EGFR-mutated non-small cell lung cancer with brain metastases: a systematic review and meta-analysis.

Sci Rep · 2024 · PMC11447023 · PMID 39358420

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

The risk of intracranial progression was significantly lower with other regimens (including 1G/3G TKIs + CT and 3G TKIs), and 1G TKIs + VEGF mAb showed a trend toward reduced intracranial progression but did not reach statistical significance.

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