Associations between maternal microbiome, metabolome and incidence of low-birth weight in Guatemalan participants from the Women First Trial.

In the present study, many of our differences were only nominally significant and did not pass multiple testing corrections, and hence should be interpreted with caution.

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Of the microbial taxa identified, Roseburia was enriched at 12 weeks in mothers of LBW compared to NW infants, although it did not reach statistical significance During pregnancy, Roseburia is lower in women with gestational diabetes and obesity ( Shen et al., 2024 ; Obuchowska et al., 2022 ).

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