Limited support for a direct connection between prebiotics and intestinal permeability - a systematic review.

Glycoconj J · 2024 · PMC11522178 · PMID 39287885

Europe PMC DOI

hedged sentences

0.0582

closest p · 1.2× alpha

0.0760

boldest claim

The sentences

close to significanceP = 0.0582so close (0.05 < p ≤ 0.1)

(2016) [ 26 ] was close to significance(P = 0.0582).

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approached significanceP = 0.0582so close (0.05 < p ≤ 0.1)

The gut microbiota composition remained largely unchanged after the intervention whereas the PCR results revealed that the Bifidobacterium levels increased in both groups; with a greater change observed in the prebiotic group, which approached significance (P = 0.0582) [ 26 ].

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did not reach statistical significanceP = 0.076so close (0.05 < p ≤ 0.1)

The study observed that after 3 months of FOS-enriched inulin treatment, the prebiotic group had a decrease (-0.005) in L/M ratio compared to the baseline values, indicating the decrease in intestinal permeability although this difference did not reach statistical significance (P = 0.076).

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