a strong trendP = .052
In addition, we observed a strong trend for a higher occurrence of nausea (52.9% vs. 27.9%; P = .052) and obstipation (5.9% vs. 0.0%; P = .057) in patients with prior antibiotic use.
In addition, we observed a strong trend for a higher occurrence of nausea (52.9% vs. 27.9%; P = .052) and obstipation (5.9% vs. 0.0%; P = .057) in patients with prior antibiotic use.
This analysis largely confirms the original results in Table 2 , except for nausea, which is now marginally non-significant ( P = .061).
Multivariable Cox regression showed a trend toward shorter survival time ( P = .089) in the antibiotic group.