Doxycycline with or without famciclovir for infectious ophthalmic and respiratory disease: a prospective, randomized, masked, placebo-controlled trial in 373 kittens.

Meanwhile, symblepharon persisted in more kittens receiving famciclovir and doxycycline than in those receiving doxycycline alone; however, this difference did not achieve significance ( P = 0.077) and was not noted for the development or resolution of symblepharon.

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Although the majority of kittens in the study (regardless of treatment, age or disease severity at study entry) achieved the defined resolution or recovery endpoints, kittens receiving famciclovir along with antibiotics had a number of statistically significant or near-significant outcomes superior to those seen in kittens receiving antibiotics only.

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The rates at which they achieved ophthalmic resolution ( P = 0.089) and recovery ( P = 0.064) also approached significance.

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